Erasing memories may stop cocaine cravings

Erasing memories may stop cocaine cravings


SIGHTS and smells that remind addicts of a previous high can induce strong cravings and make quitting tough. Now the neurons responsible for these “association memories” have been deactivated in rats. Bruce Hope and colleagues at the National Institute on Drug Abuse in Baltimore, Maryland, studied rats engineered so that their neurons released a specific enzyme whenever they produced a protein called Fos, which only happens when neurons are highly activated. This allowed them to shut down Fos-producing neurons,
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